The protein encoded by this gene is a transmembrane
glycoprotein that is a member of the protein kinase superfamily.
This protein is a receptor for members of the epidermal growth
factor family. EGFR is a cell surface protein that binds to
epidermal growth factor. Binding of the protein to a ligand induces
receptor dimerization and tyrosine autophosphorylation and leads to
cell proliferation. Mutations in this gene are associated with lung
cancer.