This gene encodes a DNA-binding protein which specifically
recognizes conserved target sequences at the breakpoint junction of
chromosomal translocations. Translin polypeptides form a multimeric
structure that is responsible for its DNA-binding activity.
Recombination-associated motifs and translin-binding sites are
present at recombination hotspots and may serve as indicators of
breakpoints in genes which are fused by translocations. These
binding activities may play a crucial role in chromosomal
translocation in lymphoid neoplasms.
