- 中文名称
Phospho-小鼠 IKKB(S701)抗体
- 英文名字
- Phospho-mouse IKKB(S701) Antibody
- 供应商
- Abgent
- 产品货号
- A-AP3851a
- 产品报价
- ￥2310/400 ul
- 产品说明书
- 点击查看
- 购买方式
- 产品新闻
- 背景资料
- NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL
(MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the
NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins
(NFKBIA, MIM 164008, or NFKBIB, MIM 604495), which inactivate
NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of
serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM
600664, or IKBKB) marks them for destruction via the ubiquitination
pathway, thereby allowing activation of the NF-kappa-B complex.
Activated NFKB complex translocates into the nucleus and binds DNA
at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or
5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G
purine; and Y is a C or T pyrimidine).
- 应用类型
- DB
- 免疫原
- O88351
- 来源宿主
- 反应性
- 保存建议
- 其他
- ABGENT
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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