This gene encodes subunit 2 of the splicing factor 3a
protein complex. The splicing factor 3a heterotrimer includes
subunits 1, 2 and 3 and is necessary for the in vitro conversion of
15S U2 snRNP into an active 17S particle that performs pre-mRNA
splicing. Subunit 2 interacts with subunit 1 through its
amino-terminus while the single zinc finger domain of subunit 2
plays a role in its binding to the 15S U2 snRNP. Subunit 2 may also
function independently of its RNA splicing function as a
microtubule-binding protein.
