This gene encodes a member of the immunoglobulin receptor
superfamily and is one of several Fc receptor-like glycoproteins
clustered on the long arm of chromosome 1. The encoded protein
contains immunoreceptor-tyrosine activation motifs and
immunoreceptor-tyrosine inhibitory motifs in its cytoplasmic domain
and may play a role in regulation of the immune system. Mutations
in this gene have been associated with rheumatoid arthritis,
autoimmune thyroid disease, and systemic lupus erythematosus.
