The protein encoded by this gene belongs to the innexin
family. Innexin family members are the structural components of gap
junctions. This protein and pannexin 1 are abundantly expressed in
central nervous system (CNS) and are coexpressed in various
neuronal populations. Studies in Xenopus oocytes suggest that this
protein alone and in combination with pannexin 1 may form cell
type-specific gap junctions with distinct properties. Multiple
transcript variants encoding different isoforms have been found for
this gene.