This gene encodes the beta-subunit of glucosidase II, an
N-linked glycan-processing enzyme in the endoplasmic reticulum
(ER). This protein is an acidic phospho-protein known to be a
substrate for protein kinase C. Mutations in this gene have been
associated with the autosomal dominant polycystic liver disease
(PCLD). Alternatively spliced transcript variants encoding distinct
isoforms have been observed.
