The protein encoded by this gene belongs to the class II
cytokine receptor family, and has been shown to be a receptor for
interleukin 22 (IL22). IL22 receptor is a protein complex that
consists of this protein and interleukin 10 receptor, beta
(IL10BR/CRFB4), a subunit also shared by the receptor complex for
interleukin 10 (IL10). This gene and interleukin 28 receptor, alpha
(IL28RA) form a cytokine receptor gene cluster in the chromosomal
region 1p36.
