Protein 4.1 of red blood cells, or 4.1R (EPB41; MIM
130500), is a multifunctional protein essential for maintaining
erythrocyte shape and membrane mechanical properties. The protein
4.1 family comprises a group of structural proteins that includes,
in addition to 4.1R, 4.1G (general type; MIM 603237), 4.1B (brain
type; MIM 605331), 4.1N (neuron type; MIM 602879), and 4.1O (ovary
type).
