The protein phosphatase-1 (PP1) catalytic subunit (PPP1CA;
MIM 176875) is regulated by targeting subunits, such as PP1R3B.
PP1R3B suppresses the rate at which PP1 dephosphorylates (i.e.,
inactivates) glycogen phosphorylase (see PYGL; MIM 232700) and
enhances the rate at which it activates glycogen synthase (see
GYS2; MIM 138571) (Doherty et al., 1995 [PubMed 7498521]).[supplied
by OMIM].