This gene is a member of the cyclophilin family of
peptidylprolyl isomerases. The cyclophilins are a highly conserved
ubiquitous family, members of which play an important role in
protein folding, immunosuppression by cyclosporin A, and infection
of HIV-1 virions. This protein interacts with the proteinase
inhibitor eglin c and is localized in the nucleus. Multiple
transcript variants encoding different isoforms have been found for
this gene.
