Malate dehydrogenase catalyzes the reversible oxidation of
malate to oxaloacetate, utilizing the NAD/NADH cofactor system in
the citric acid cycle. The protein encoded by this gene is
localized to the mitochondria and may play pivotal roles in the
malate-aspartate shuttle that operates in the metabolic
coordination between cytosol and mitochondria. [provided by
RefSeq].
