The protein encoded by this gene belongs to the
G-protein-coupled receptor family . It is a receptor for the CC
chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group
of small polypeptide, structurally related molecules that regulate
cell trafficking of various types of leukocytes. The chemokines
also play fundamental roles in the development, homeostasis, and
function of the immune system, and they have effects on cells of
the central nervous system as well as on endothelial cells involved
in angiogenesis or angiostasis.
