The product of the MND1 gene associates with HOP2 (MIM
608665) to form a stable heterodimeric complex that binds DNA and
stimulates the recombinase activity of RAD51 (MIM 179617) and DMC1
(MIM 602721) (Chi et al., 2007 [PubMed 17639080]). Both the MND1
and HOP2 genes are indispensable for meiotic
recombination.
