GPT (MIM 138200) and GPT2 (EC 2.6.1.2), also known as
alanine transaminases, are pyridoxal enzymes that catalyze the
reversible transamination between alanine and 2-oxoglutarate to
form pyruvate and glutamate. By mediating the conversion of these 4
major intermediate metabolites, these transaminases have roles in
gluconeogenesis and in amino acid metabolism.
