The protein encoded by this gene is a type-1 membrane
glycoprotein, which contains two immunoglobulin domains, and thus
belongs to the immunoglobulin superfamily. Studies of the related
genes in mouse and rat suggest that this gene may regulate myeloid
cell activity and delivers an inhibitory signal for the macrophage
lineage in diverse tissues. Multiple alternatively spliced
transcript variants that encode different isoforms have been found
for this gene.