- 中文名称
MAPK14抗体
- 英文名字
- MAPK14 Antibody
- 供应商
- Abgent
- 产品货号
- A-AO1867a
- 产品报价
- ￥3850/0.1mg
- 产品说明书
- 点击查看
- 购买方式
- 产品新闻
- 背景资料
- The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. ; ; ;
- 应用类型
- WB
- 免疫原
- Q16539
- 来源宿主
- С
- 反应性
- 保存建议
- 其他
- ABGENT
- 注意
-
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