- 中文名称
Phospho-Ser358 Eukaryotic Elongation Factor 1 alpha 2 (eEF1A2)抗体
- 英文名字
- Phospho-Ser358 Eukaryotic Elongation Factor 1 alpha 2 (eEF1A2) Antibody
- 供应商
- Abgent
- 产品货号
- A-AN1251
- 产品报价
- ¥3685/100 ul

- 产品说明书
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- 购买方式
- 产品新闻

- 背景资料
- Eukaryotic Elongation Factor eEF1A exists in two variant forms, eEF1A1 and eEF1A2. While eEF1A1 is almost ubiquitously expressed in humans, eEF1A2 is predominantly found in heart, brain, and skeletal muscle (Knudsen et al., 1993). Expression of eEF1A2 may have a role in ovarian cancer, as its expression is drastically increased in human ovarian tumors (Anand et al., 2002). Due to differences in structural models between the two isoforms, eEF1A1 and eEF1A2 likely have variant-specific phosphorylation sites (Soares et al., 2009). Ribosome-associated JNK phosphorylates Ser358 on eEF1A2 to promote degradation of newly synthesized polypeptides by the proteasome (Gandin et al., 2013).
- 应用类型
- WB
- 免疫原
- Q05639
- 来源宿主
- 反应性
- 保存建议
- 其他
- ABGENT

- 注意
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