Stargazin is a member of the transmembrane AMPAR regulatory
proteins (TARP) family and is involved in glut
amate receptor trafficking. It has been recently
demonstrated (Tomita et al., 2005; Priel et al., 2005) that the interaction between stargazin and
AMPA receptors is critical for the correct localization of the receptors at the synapse.
Phosphorylation of the stargazin protein at Thr 321 by Protein Kinase A regulates its interaction
with PSD-95 and synaptic targeting of AMPA receptors (Choi et al., 2002).