Synaptophysin 2, also known as Synaptoporin, is a component of the
synaptic vesicle membrane and thought to play an important role in synaptic vesicle trafficking
(Dai et al., 2003). It is highly homologous to Synaptophysin 1, yet differs in expression.
Whereas Synaptophysin 1 is ubiquit
iously expressed, Synaptophysi
n 2 is concentrated in the
mossy fiber synapses of the hippocampus (Grabs et al., 1994; Singec et al., 2002).
