- 中文名称
Sodium Calcium Exchanger 1 抗体
- 英文名字
- Sodium Calcium Exchanger 1 Antibody
- 供应商
- Abgent
- 产品货号
- A-AN1058
- 产品报价
- ￥3685/100 ug
- 产品说明书
- 点击查看
- 购买方式
- 产品新闻
- 背景资料
- Ca
2+
plays a critical role in intracellular signaling and thus regulation
of calcium balance is critical for the maintenance of this signaling function. The plasma
membrane Na
+
/Ca
2+
(NaCX) exchangers mediate Na
+
-dependent Ca
2+
efflux in a wide variety of
cell types. NaCX can move Ca
2+
either into or out of cells, depending on the net Na
+
, Ca
2+
, and
K
+
gradient across the membrane. In mammals, at least 5 distinct genes code for the
exchangers: Three NaCX (NaCX-1, NaCX-2, an
d NaCX-3), and two in the NaCKX family
(NaCKX-1 and NaCKX-2). NaCX-1 is most prominently expressed in the heart where it plays a
major role in excitation-contraction coupling (Matsuoka et al., 1993). NACX-1 may also be a
target for protection of the heart and brain from
ischemia and reperfusion injury (Hagihara et al.,
2005; Bano et al., 2005; Choi, 2005).
- 应用类型
- WB
- 免疫原
- Q01728
- 来源宿主
- С
- 反应性
- 保存建议
- 其他
- ABGENT
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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