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中文名称

ACHE抗体(C端) (Ascites)

英文名字
ACHE Antibody (C-term) (Ascites)
供应商
Abgent
产品货号
A-AM2184a
产品报价
¥2310/0.1 ml
产品说明书
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背景资料
Acetylcholinesterase hydrolyzes the neurotransmitter,
acetylcholine at neuromuscular junctions and brain cholinergic
synapses, and thus terminates signal transmission. It is also found
on the red blood cell membranes, where it constitutes the Yt blood
group antigen. Acetylcholinesterase exists in multiple molecular
forms which possess similar catalytic properties, but differ in
their oligomeric assembly and mode of cell attachment to the cell
surface. It is encoded by the single ACHE gene, and the structural
diversity in the gene products arises from alternative mRNA
splicing, and post-translational associations of catalytic and
structural subunits. The major form of acetylcholinesterase found
in brain, muscle and other tissues is the hydrophilic species,
which forms disulfide-linked oligomers with collagenous, or
lipid-containing structural subunits. The other, alternatively
spliced form, expressed primarily in the erythroid tissues, differs
at the C-terminal end, and contains a cleavable hydrophobic peptide
with a GPI-anchor site. It associates with the membranes through
the phosphoinositide (PI) moieties added post-translationally.
应用类型
WB
免疫原
P22303
来源宿主
С
反应性
保存建议
其他
ABGENT
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