This gene encodes the D2 subtype of the dopamine receptor.
This G-protein coupled receptor inhibits adenylyl cyclase activity.
A missense mutation in this gene causes myoclonus dystonia; other
mutations have been associated with schizophrenia. Alternative
splicing of this gene results in two transcript variants encoding
different isoforms. A third variant has been described, but it has
not been determined whether this form is normal or due to aberrant
splicing.
