This gene encodes an androgen receptor coactivator. The
encoded protein interacts with the androgen receptor in a
ligand-dependent manner to enhance its transcriptional activity.
Chromosomal translocations between this gene and the ret tyrosine
kinase gene, also located on chromosome 10, have been associated
with papillary thyroid carcinoma. Alternatively spliced transcript
variants have been described. Pseudogenes are present on
chromosomes 4, 5, 10, and 14.
