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中文名称

抗CIDEA / CIDE-A抗体(aa200-217) ALS11531

英文名字
Anti-CIDEA / CIDE-A Antibody (aa200-217) ALS11531
供应商
Abgent
产品货号
A-ALS11531
产品报价
¥3420/50 ug
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背景资料
Acts as a CEBPB coactivator in mammary epithelial cells to control the expression of a subset of CEBPB downstream target genes, including ID2, IGF1, PRLR, SOCS1, SOCS3, XDH, but not casein. By interacting with CEBPB, strengthens the association of CEBPB with the XDH promoter, increases histone acetylation and dissociates HDAC1 from the promoter (By similarity). Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair and occurs at a lower rate than that promoted by CIDEC. When overexpressed, induces apoptosis. The physiological significance of its role in apoptosis is unclear.
应用类型
WB
免疫原
O60543
来源宿主
反应性
保存建议
其他
ABGENT
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