- 中文名称
抗CIDEA / CIDE-A抗体(aa200-217) ALS11531
- 英文名字
- Anti-CIDEA / CIDE-A Antibody (aa200-217) ALS11531
- 供应商
- Abgent
- 产品货号
- A-ALS11531
- 产品报价
- ¥3420/50 ug

- 产品说明书
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- 产品新闻

- 背景资料
- Acts as a CEBPB coactivator in mammary epithelial cells to control the expression of a subset of CEBPB downstream target genes, including ID2, IGF1, PRLR, SOCS1, SOCS3, XDH, but not casein. By interacting with CEBPB, strengthens the association of CEBPB with the XDH promoter, increases histone acetylation and dissociates HDAC1 from the promoter (By similarity). Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair and occurs at a lower rate than that promoted by CIDEC. When overexpressed, induces apoptosis. The physiological significance of its role in apoptosis is unclear.
- 应用类型
- WB
- 免疫原
- O60543
- 来源宿主
- 反应性
- 保存建议
- 其他
- ABGENT

- 注意
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