- 中文名称
抗CD209 / DC-SIGN抗体(Internal) ALS11410
- 英文名字
- Anti-CD209 / DC-SIGN Antibody (Internal) ALS11410
- 供应商
- Abgent
- 产品货号
- A-ALS11410
- 产品报价
- ¥3420/50 ug

- 产品说明书
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- 购买方式
- 产品新闻

- 背景资料
- Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response. Probably recognizes in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens, including HIV-1 gp120, HIV-2 gp120, SIV gp120, ebolavirus glycoproteins, cytomegalovirus gB, HCV E2, dengue virus gE, Leishmania pifanoi LPG, Lewis-x antigen in Helicobacter pylori LPS, mannose in Klebsiella pneumonae LPS, di-mannose and tri- mannose in Mycobacterium tuberculosis ManLAM and Lewis-x antigen in Schistosoma mansoni SEA.
- 应用类型
- WB
- 免疫原
- Q9NNX6
- 来源宿主
- 反应性
- 保存建议
- 其他
- ABGENT

- 注意
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