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一抗
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中文名称

抗MMP13抗体(Internal) ALS10394

英文名字
Anti-MMP13 Antibody (Internal) ALS10394
供应商
Abgent
产品货号
A-ALS10394
产品报价
¥3420/50 ug
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背景资料
Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.
应用类型
IHC-P
免疫原
P45452
来源宿主
反应性
保存建议
其他
ABGENT
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