- 中文名称
CD1a抗体[克隆O10+C1A/711]
- 英文名字
- CD1a Antibody [Clone O10+C1A/711]
- 供应商
- Abgent
- 产品货号
- A-AH10303
- 产品报价
- ¥2870/100 ug

- 产品说明书
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- 购买方式
- 产品新闻

- 背景资料
- At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5, anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. Anti-CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa).
- 应用类型
- FC
- 免疫原
- P06126
- 来源宿主
- С
- 反应性
- 保存建议
- 其他
- ABGENT

- 注意
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