- 中文名称
ACTH抗体[克隆2F6]
- 英文名字
- ACTH Antibody [Clone 2F6]
- 供应商
- Abgent
- 产品货号
- A-AH10027
- 产品报价
- ¥2870/100 ug

- 产品说明书
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- 购买方式
- 产品新闻

- 背景资料
- ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This MAb is specific to Synacthen (aa1-24 of ACTH); does not react with CLIP (aa17-39 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH.
- 应用类型
- ELISA
- 免疫原
- P01189
- 来源宿主
- С
- 反应性
- 保存建议
- 其他
- ABGENT

- 注意
-
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