- 中文名称
大鼠TRPV1 (胞外)抗体
- 英文名字
- rat TRPV1 (extracellular) Antibody
- 供应商
- Abgent
- 产品货号
- A-AG1453
- 产品报价
- ￥3025/25 ul
- 产品说明书
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- 购买方式
- 产品新闻
- 背景资料
- TRP channels are a large family (about 28 genes) of plasma membrane, non-selective cationic channels that are either specifically or ubiquitously expressed in excitable and non-excitable cells.1
According to IUPHAR the TRP family comprises of three main subfamilies on the basis of sequence homology; TRPC, TRPM and TRPV (to date, three extra subfamilies are considered to belong to the TRP family; the TRPA, TRPML, and TRPP).1-4 The TRPV subfamily consists of six members, TRPV1-6.5
TRPV1 channel has many activators among them heat, protons, vanilloids like capsaicin, reiniferatoxin (RTX), and lipids. This channel is associated with tissue injury and inflammation.6,7
TRPV1 is expressed predominantly in nociceptors and in sensory neurons.
Recent studies demonstrated involvement of TRPV1 in apoptosis where inhibition of the receptor prevented apoptosis.8,9
Alomone Labs is pleased to offer a highly specific antibody directed against an extracellular epitope of the rat TRPV1 channel. Anti-Rat TRPV1 (extracellular) antibody (#AG1453) can be used for western blot and immunohistochemistry applications. It has been designed to recognize only rat TRPV1 samples.
- 应用类型
- WB
- 免疫原
- O35433
- 来源宿主
- 反应性
- 保存建议
- 其他
- ABGENT
- 注意
-
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