- 中文名称
GABA(A) gamma1 Receptor抗体
- 英文名字
- GABA(A) gamma1 Receptor Antibody
- 供应商
- Abgent
- 产品货号
- A-AG1270
- 产品报价
- ￥4125/50 ul
- 产品说明书
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- 购买方式
- 产品新闻
- 背景资料
- The neurotransmitter GABA (γ-aminobutyric acid) inhibits the activity of signal-receiving neurons by interacting with the GABAA receptor on these cells1. There are two major types of GABA receptors: the ionotropic GABAA (GABAA R) and the metabotropic GABAB receptors. GABAA R belongs to the ligand gated ion channel superfamily1,2.
The binding of GABA to its GABAA receptor results in conformational changes that open a Cl- channel, producing an increase in membrane conductance, resulting in inhibition of neural activity2,3.
They are composed of heteropentamer, with all of the five subunits contributing to the pore formation. To date, eight subunit isoforms have been cloned: α, β, γ, δ, ε, π, θ, and ρ1. The native GABAA receptor, in most cases, consists of 2α, 2β and 1γ subunit. Three γ subunits genes have been identified in mammals.
mRNA of the γ1 subunit is detected in the amygdala and septum4.
Alomone Labs is pleased to offer a highly specific antibody directed against an epitope of rat GABA(A) γ1 subunit. Anti-GABA(A) γ1 Receptor antibody (#AG1270) can be used in western blot analysis and was designed to recognize GABA(A) γ1 from human, rat and mouse samples.
- 应用类型
- WB
- 免疫原
- P23574
- 来源宿主
- 反应性
- 保存建议
- 其他
- ABGENT
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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