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中文名称

Galanin Receptor Type 2抗体

英文名字
Galanin Receptor Type 2 Antibody
供应商
Abgent
产品货号
A-AG1240
产品报价
¥4125/50 ul
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背景资料
Galanin is a neuropeptide, consisting of 29-30 amino acid residues, involved in the regulation of cognition, mood, feeding, seizure activity and pain. Galanin exerts its action via three known Galanin Receptors, the Galanin Receptor Type 1 (GALR1), Galanin Receptor Type 2 (GALR2) and Galanin Receptor Type 3 (GALR3). The Galanin Receptors belong to the G-Protein Coupled Receptor superfamily.1-4

GALR2 is widely expressed in the brain (with highest levels of mRNA found in the hypothalamus, hippocampus, amygdala and pyriform cortex) and in peripheral tissues such as the small intestine, heart, kidney, and liver. GALR2 high levels of expression were also found in rat dorsal root ganglia.1

GALR2 activation increases inositol phosphate hydrolysis, mediates the release of Ca2+ into the cytoplasm from intracellular stores, and opens Ca2+-dependent chloride channels in a PTX-resistant manner, indicating that GALR2 couples to Gq/11 proteins.5

Alomone Labs is pleased to offer a highly specific antibody directed against an intracellular epitope of mouse Galanin Receptor type 2 (GALR2). Anti-Galanin Receptor Type 2 antibody (#AG1240) can be used for Western blot analysis and immunohis
应用类型
WB
免疫原
O88854
来源宿主
反应性
保存建议
其他
ABGENT
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