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中文名称

P2Y4 Receptor抗体

英文名字
P2Y4 Receptor Antibody
供应商
Abgent
产品货号
A-AG1072
产品报价
¥4125/50 ul
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背景资料
The P2Y receptors belong to the G-protein coupled receptors superfamily.  P2Y receptors mediate the actions of the extracellular nucleotides (ATP, ADP, UTP and UDP) and regulate several physiologic responses, among them, cardiac function, platelet aggregation and SMC proliferation.1

The mammalian P2Y family currently includes eight functional receptors; P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, P2Y13, and the UDP-glucose receptor, now renamed P2Y14.2-4

The P2Y4-receptor is highly expressed in the placenta and with lower levels at lung and vascular smooth muscle.5

The human P2Y4 receptor is highly selective to UTP while rat P2Y4 receptor is equally activated by both UTP and ATP and also by other triphosphate nucleotides such as Ap4A.5

Recently it has been shown that P2Y4 receptor is involved in differentiation and cell death of human neuroblastoma SH-SY5Y cells.6

Alomone Labs is pleased to offer a highly specific antibody directed against the C terminus domain of the rat P2Y4 receptor. Anti-P2Y4 Receptor antibody (#AG1072) can be used in western blot analysis, immunoprecipitation, indirect flow cytometry, immunocytochemistry and immunohistochemistry, and recognizes P2Y4 in rat samples.
应用类型
WB
免疫原
O35811
来源宿主
反应性
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ABGENT
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