- 中文名称
P2X7 Receptor (胞外)抗体
- 英文名字
- P2X7 Receptor (extracellular) Antibody
- 供应商
- Abgent
- 产品货号
- A-AG1071
- 产品报价
- ￥4125/50 ul
- 产品说明书
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- 购买方式
- 产品新闻
- 背景资料
The P2X7 receptor is a member of the ionotropic P2X receptor family that is activated by ATP.
To date, this family is composed of seven cloned receptor subtypes, named P2X1-P2X7.
The different P2X receptors show distinct expression patterns. P2X1-6 have been found in the central and peripheral nervous system, while the P2X7 receptor is found in cells of the immune system, particularly antigen presenting cells, and microglia. The P2X7 receptor mediates the release of proinflamatory cytokines, stimulation of transcription factors and may also have an important role in apoptosis.1-3
Different techniques have been used to characterize the P2X7 receptor. Most of them investigated pores, ion channels (electrophysiology) and membrane alterations (calcium microfluorometry, dye uptake, membrane depolarization and ion influx analysis). With the introduction of flow cytometry, it is now possible to analyze multiple cell parameters such as cell cycle, cell membrane alteration, calcium influx and cell phenotype.4
- 应用类型
- WB
- 免疫原
- Q9Z1M0
- 来源宿主
- 反应性
- 保存建议
- 其他
- ABGENT
- 注意
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