- 中文名称
P2Y12 Receptor抗体
- 英文名字
- P2Y12 Receptor Antibody
- 供应商
- Abgent
- 产品货号
- A-AG1068
- 产品报价
- ￥4125/50 ul
- 产品说明书
- 点击查看
- 购买方式
- 产品新闻
- 背景资料
The P2Y receptors belong to the G-protein coupled receptors superfamily.
They mediate the actions of the extracellular nucleotides (ATP, ADP, UTP AND UDPA. Eight functional mammalian P2Y receptors have been described: P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, P2Y13, and the UDP-glucose receptor, now renamed P2Y14.1-3
The P2Y12 receptor is co-expressed with P2Y1 receptor on platelets leading to shape change, aggregation, and rise in intracellular Ca2+ upon activation.
The only other expression of P2Y12 was found in brain, according to results of reverse transcription-polymerase chain reaction and northern blotting.4 The P2Y12 receptor has become a target for potential therapeutic drugs for the treatment of thromboembolism and other clotting disorders.4
- 应用类型
- WB
- 免疫原
- Q9H244
- 来源宿主
- 反应性
- 保存建议
- 其他
- ABGENT
- 注意
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