- 中文名称
P2X2 Receptor (胞外)抗体
- 英文名字
- P2X2 Receptor (extracellular) Antibody
- 供应商
- Abgent
- 产品货号
- A-AG1061
- 产品报价
- ￥4125/50 ul
- 产品说明书
- 点击查看
- 购买方式
- 产品新闻
- 背景资料
- The P2X receptors belong to the ligand-gated ion channel family and are activated by extracellular ATP.
The structure and function of the P2X receptors, which were mainly investigated using in vitro models, show their involvement in synaptic communication, cell death, and differentiation.
Seven mammalian P2X receptor subtypes (P2X1–P2X7) have been identified and cloned1-3. All P2X receptor subtypes share the same structure of intracellular N- and C-termini, two membrane-spanning domains and a large extracellular loop. All P2X subtypes can assemble to form homomeric or heteromeric functional channels with the exception of P2X6, which only seems to function as part of a heteromeric complex4-9.
The various mammalian P2X receptors show distinct expression patterns. P2X1-6 have been found in the central and peripheral nervous system, while the P2X7 receptor is predominantly found in cells of the immune system4. The P2X2 receptor subtype has a widespread tissue distribution in autonomic neurons, but it is generally found to be co-expressed with one or more subtypes.
mRNA of the P2X1, P2X2, P2X3, and P2X6 receptors is found in neurons of dorsal root ganglia (DRG), trigeminal, and nodose ganglia where heteromeric P2X2/P2X3 receptors are found10.
Alomone Labs is pleased to offer a highly specific antibody directed against an extracellular epitope of rat P2X2 Receptor. Anti-P2X2 Receptor (extracellular) antibody (#AG1061) can be used in western blot and immunocytochemistry applications. It has been designed to recognize P2X2 Receptor from mouse and rat samples. It will not recognize human P2X2.
- 应用类型
- WB
- 免疫原
- P49653
- 来源宿主
- 反应性
- 保存建议
- 其他
- ABGENT
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
-
