- 中文名称
Somatostatin Receptor Type I (胞外)抗体
- 英文名字
- Somatostatin Receptor Type I (extracellular) Antibody
- 供应商
- Abgent
- 产品货号
- A-AG1021
- 产品报价
- ¥4125/50 ul

- 产品说明书
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- 购买方式
- 产品新闻

- 背景资料
- Somatostatin is a small cyclic peptide that is widely expressed throughout the central nervous system and peripheral tissues.1 In peripheral tissues, somatostatin exerts inhibitory effects on secretion processes, whereas in the brain it acts as a neurotransmitter in both stimulatory and inhibitory manner.1, 2
Somatostatin mediates its action via six high affinity G-protein coupled receptors (SSTR1, SSTR2a, SSTR2b, SSTR3, SSTR4 and SSTR5) which are encoded by five genes.1,2 Expression of the different receptors is developmentally regulated in a time and tissue-specific manner.2 Somatostatin receptors have been found on a variety of neuroendocrine tumors, such as paragangliomas, carcinoids and breast tumors.3 Synthetic peptide derivatives of somatostatin have been successfully used in the treatment of neuroendocrine malignancies and in in vivo imaging of tumors that are positive to somatostatin receptors.4
Alomone Labs is pleased to offer a highly specific antibody directed against the N-terminus domain of the rat SSTR1. Anti-Somatostatin Receptor Type 1 antibody (#AG1021), can be used in western blot analysis, and recognizes SSTR1 in rat samples.
- 应用类型
- WB
- 免疫原
- P28646
- 来源宿主
- 反应性
- 保存建议
- 其他
- ABGENT

- 注意
-
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