- 中文名称
Sphingosine 1-Phosphate Receptor 1 (胞外)抗体
- 英文名字
- Sphingosine 1-Phosphate Receptor 1 (extracellular) Antibody
- 供应商
- Abgent
- 产品货号
- A-AG1015
- 产品报价
- ￥4125/50 ul
- 产品说明书
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- 购买方式
- 产品新闻
- 背景资料
- Lysophospholipids constitute a group of important lipid mediators; lysophosphatidic acid (LPA) a glycerolysophospholipid and sphingosine 1-phosphate (SIP), a lysosphingolipid. Sphingosine 1-phosphate is a bioactive lipid derived from metabolism of sphingomyelin1. Sphingosine 1-phosphate is implicated in the regulation of many cellular functions including proliferation, apoptosis, survival, adhesion, differentiation, and migration2. Sphingosine 1-phosphate exerts its activity through five distinct G-protein-coupled receptors, (also named endothelial differentiation gene receptors - EDG); S1PR1 (EDG-1), S1PR2 (EDG-5), S1PR3 (EDG-3), S1PR4 (EDG-6), and S1PR5 (EDG-8)3.
Sphingosine 1-Phosphate Receptor 1 (S1PR1) is ubiquitously expressed. S1PR1 mRNA is detected in the brain, heart, spleen, liver, lung, thymus, kidney, skeletal muscle and lymphoid tissues4.
Knockout of the gene encoding S1PR1 is lethal and therefore makes in vivo studies difficult 5.
Alomone Labs is pleased to offer a highly specific antibody directed against an extracellular epitope of the human Sphingosine 1-Phosphate Receptor 1. Anti-Sphingosine 1-Phosphate Receptor 1 (extracellular) antibody, (#AG1015) can be used in western blot analysis, immunohistochemistry and immunocytochemistry applications. It has been designed to recognize Sphingosine 1-Phosphate Receptor 1 from human, rat and mouse samples.
- 应用类型
- WB
- 免疫原
- P21453
- 来源宿主
- 反应性
- 保存建议
- 其他
- ABGENT
- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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