- 中文名称
5-Hydroxytryptamine Receptor 1A抗体
- 英文名字
- 5-Hydroxytryptamine Receptor 1A Antibody
- 供应商
- Abgent
- 产品货号
- A-AG1012
- 产品报价
- ￥4125/50 ul
- 产品说明书
- 点击查看
- 购买方式
- 产品新闻
- 背景资料
- Serotonin [5-hydroxytryptamine (5-HT1)] is an important neurotransmitter in the CNS that exerts its neuronal activity via 5-HT receptors.
5-HT receptors are subdivided into seven families termed 5-HT1 through 5-HT7.1 The 5-HT receptor families belong to the G-Protein Coupled receptor superfamily with the exception of 5-HT3 receptor class which belongs to the ligand-gated ion channels. 2
The 5-HT1 receptor class comprises of five different receptors (5-HT1A, 5-HT1B, 5-HT1D, 5-HT1e AND 5-HT1F) which share 41-63% overall sequence identity and couple preferentially to Gi/Go to inhibit cAMP formation.2
The 5-HT1A receptor is the most widespread of all the 5-HT receptors. In the central nervous system, 5-HT1A receptors exist in the cerebral cortex, hippocampus, septum, amygdala and raphe nucelus in high densities, and was also demonstrated in a variety of tissues from various species.2,3
Activation of 5-HT1A receptor decreases blood pressure and heart rate, involved in learning, memory, relieving anxiety and depression. 1,4
Alomone Labs is pleased to offer a highly specific antibody directed against an intracellular epitope of the rat 5-Hydroxytryptamine Receptor 1A (5-HT1A). Anti-5-Hydroxytryptamine Receptor 1A antibody (#AG1012) can be used for western blot and immunohistochemistry applications. It has been designed to recognize 5-Hydroxytryptamine Receptor 1A from rat and mouse samples.
- 应用类型
- WB
- 免疫原
- P19327
- 来源宿主
- 反应性
- 保存建议
- 其他
- ABGENT
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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