- 中文名称
Superoxide Dismutase 2 (SOD-2)抗体(2A1)
- 英文名字
- Superoxide Dismutase 2 (SOD-2) Antibody (2A1)
- 供应商
- Abgent
- 产品货号
- A-ABV11162
- 产品报价
- ￥3920/100 ul
- 产品说明书
- 点击查看
- 购买方式
- 产品新闻
- 背景资料
- Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn-SOD/SOD-1), mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, Zn-SOD (EC-SOD/SOD-3). SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit. The manganese containing 80 kDa tetrameric enzyme SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain. SOD3 is a heparin-binding multimer of disulfide-linked dimers, primarily expressed in human lungs, vessel walls
and airways. SOD4 is a copper chaperone for superoxide dismutase (CCS), which specifically delivers Cu to copper/zinc superoxide dismutase. CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor. SOD2 destroys radicals which are normally produced within the cells and which are toxic to biological systems.
- 应用类型
- WB
- 免疫原
- P04179
- 来源宿主
- С
- 反应性
- 保存建议
- 其他
- ABGENT
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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