- 中文名称
HSP70抗体
- 英文名字
- HSP70 antibody
- 供应商
- Abgent
- 产品货号
- A-ABV11073
- 产品报价
- ¥2990/100 ug

- 产品说明书
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- 购买方式
- 产品新闻

- 背景资料
- Hsp70, one class of stress proteins, is comprised of multiple members, all of which bind ATP in vitro, but are localized within different intracellular compartments. These include: a) the constitutive Hsc70 (or cognate) present within the cytosol/nucleus; b) the highly stress-inducible Hsp70 present within the cytosol/ nucleus/nucleolus; c) the constitutive glucose regulated 78 kDa (or BiP) protein present within the lumen of the endoplasmic reticulum; and d) the glucose regulated 75 kDa protein present within the mitochondria. Hsp70 is typically not expressed in the cell under normal growth conditions, but is expressed at high levels in the cell experiencing stress. Consequently, detection of Hsp70 using an antibody specific for the inducible form is quite useful in ascertaining whether a stress response has occurred in the cell. It should be noted, however, that there is a constitutive level of Hsp70 expression in some cell types such as primates, e.g., human and monkey. Nevertheless increased expression of Hsp70 is observed in such cells following stress.
- 应用类型
- WB
- 免疫原
- P08107
- 来源宿主
- 反应性
- 保存建议
- 其他
- ABGENT

- 注意
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