- 中文名称
MLL1抗体
- 英文名字
- MLL1 Antibody
- 供应商
- Abgent
- 产品货号
- A-ABV10615
- 产品报价
- ¥3220/100 ul

- 产品说明书
- 点击查看
- 购买方式
- 产品新闻

- 背景资料
- Eukaryotic RNA polymerase II mediates the synthesis of mature and functional messenger RNA. This is a multistep process, called the transcription cycle, that includes five stages: preinitiation, promoter, clearance, elongation and termination. Elongation is thought to be a critical stage for the regulation of gene expression. ELL (11-19 lysine-rich leukemia protein, also designated MEN) functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. Also, ELL is thought to regulate cellular proliferation. ELL is abundantly expressed in peripheral blood leukocytes, skeletal muscle, placenta and testis, and has lower expression in spleen, thymus, heart, brain, lung, kidney, liver and ovary. The gene encoding human ELL, which maps to chromosome 19p13.1, is one of several genes which undergo translocation with the MLL gene on chromosome 11q23 in acute myeloid leukemia. MLL (myeloid/lymphoid leukemia, also designated ALL-1 and HRX) regulates embryonal and hematopoietic development.
- 应用类型
- WB
- 免疫原
- Q03164
- 来源宿主
- 反应性
- 保存建议
- 其他
- ABGENT

- 注意
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