Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway。 With MAP3K3/MKK3, catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinases p38 MAPK11, MAPK12, MAPK13 and MAPK14 and plays an important role in the regulation ofncellular responses to cytokines and all kinds of stresses。
应用类型
IHC (5 µg/ml), IP (4 µg/ml), WB (4 µg/ml, colorimetric)
免疫原
Synthetic peptide corresponding to a portion of human MEK6.