Induces apoptosis and anoikis。 Isoform BimL is more potent than isoform BimEL。 Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS。 Isoform Bim-gamma induces apoptosis。 Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway。 Isoform BimAC and isoform BimABC lack the ability to induce apoptosis。
应用类型
ELISA, FC, ICC, IHC, IP (2 µg/ml), WB (1-5 µg/ml)
免疫原
Synthetic peptide corresponding to aa 20-40 (Q20PAERPPQLRPGAPTSLQTEP40) of mouse BimL.