B7 homolog 3 (B7-H3), a member of the immunoglobulin superfamily, is also known CD276, which contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domains. B7-H3 may participate in the regulation of T-cell-mediated immune response. B7-H3 also plays a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. Furthermore, B7-H3 is involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. It could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy.
序列
提供的Human CellExp™B7-H3 / CD276,人类重组Human CellExp™ B7-H3 / CD276, Human recombinant是Biovision品牌中国区域总代理艾美捷科技产品,具体的蛋白序列可查看提供的英文版本产品说明书。
来源宿主
提供的Human CellExp™B7-H3 / CD276,人类重组Human CellExp™ B7-H3 / CD276, Human recombinant产品来源宿主,查看该产品说明书,或者在线咨询我们。
溶解建议
Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/ml