T-cell-specific surface glycoprotein CD28 is also known as TP44, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2). When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.
序列
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来源宿主
提供的Human CellExp™CD28,人类重组Human CellExp™ CD28, Human recombinant产品来源宿主,查看该产品说明书,或者在线咨询我们。
溶解建议
Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/ml