Ro 3-1314 is an inhibitor of both COX and lipoxygenase. Ro 3-1314 inhibits ram seminal vesicle COX with a Ki of 0.6 uM. It is a more effective inhibitor of COX-1 than of 15-LO, inhibiting 95% and 68%, respectively, of these enzymatic activities when used at a concentration of 48 uM.
产品描述
Ro 3-1314 is an inhibitor of both COX and lipoxygenase.{1260,1261} Ro 3-1314 inhibits ram seminal vesicle COX with a Ki of 0.6 uM.{1260} It is a more effective inhibitor of COX-1 than of 15-LO, inhibiting 95% and 68%, respectively, of these enzymatic activities when used at a concentration of 48 uM.{1261}