Dihomo-.gamma.-linolenic acid (DGLA) is a metabolite produced by chain elongation of the essential fatty acid .gamma.-linolenic acid. Ethyl DGLA is an esterified version of the free acid which is less water soluble, but more amenable for the formulation of DGLA-containing diets and dietary supplements. DGLA has been advanced as a possible treatment for various inflammatory disorders. Evening primrose oil is a DGLA-rich nutraceutical which has been advocated for such uses.
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DGLA is a metabolite produced by chain elongation of the essential fatty acid .gamma.-linolenic acid. Ethyl DGLA is an esterified version of the free acid which is less water soluble, but more ammenable for the formulation of DGLA-containing diets and dietary supplements. DGLA has been advanced as a possible treatment for various inflammatory disorders.{2361,1398} Evening primrose oil is a DGLA-rich nutraceutical which has been advocated for such uses.