5,6-dehydro Arachidonic acid is an analog of arachidonic acid with an acetylene in the 5,6 position. It inhibits 5-LO in rat basophilic leukemia cells, with a Ki value of 15 uM. In guinea pig leukocytes, 5-LO is inhibited by 5,6-dehydro arachidonic acid with an IC50 value of 10 uM.
产品描述
An analog of AA with the triple bond in the 5,6 position; inhibitor of 5-LO (Ki = 10-15 uM)