Agmatine is a natural polyamine formed by the enzymatic decarboxylation of arginine.{26562} It can be converted to putrescine by agmatinase or to guanidinobutyric acid by diamine oxidase and aldehyde dehydrogenase. Agmatine has numerous modulatory actions, particularly in pathways related to diabetes, immunity, and neurophysiology.{26562} N-Acetylagmatine is a potential monoacetylated derivative of agmatine. The enzyme-mediated acetylation of polyamines is commonly considered a degradative step, with monoacetylated polyamines detected in the urine.{26562,26560,26563} However, monoacetylated polyamines can stimulate diamine oxidase activity, suggesting that N-acetylagmatine might have physiologically important actions.{26561}
产品描述
A potential monoacetylated derivative of the natural polyamine agmatine
